The potential spread of COVID-19 in the ill-prepared Gaza Strip has become a major source of concern for Palestinians. The announced cases of inflicting with COVID-19 are all among quarantined people, so the situation appears under control. Despite the reassuring news, the preventive measures taken to prevent the spread of COVID-19 in the Gaza Strip affected the lives of many families, as well as many sectors including the industrial and commercial ones. Gaza is already very weak economically, with high levels of poverty, and the imposed restrictions aggravates the condition. Many workers lost their work chances and numerous livelihood were closed, left many unemployed. The families that are in excessive need for food parcels and essential needs increase, putting their lives at risk during this pandemic.